KETAMINE AND RAPID-ACTING ANTIDEPRESSANTS: A NEW ERA IN THE BATTLE AGAINST DEPRESSION AND SUICIDE [VERSION 1; REFEREES: 3 APPROVED]

Ketamine and rapid-acting antidepressants: a new era in the battle against depression and suicide [version 1; referees: 3 approved]

Therapeutic medications for the treatment of depression have serious limitations, particularly delayed onset and low rates of efficacy.However, the discovery that a single subanesthetic dose of ketamine, a glutamate NMDA receptor channel blocker, can produce a rapid (within hours) antidepressant response that is sustained (about 1 week), even in pa

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Context and Animacy Play a Role in Dynamic Decision-Making

Perception, judgment, and reasoning are all processes that are sensitive to cues to animacy (i.e.the presence of signals that indicate an object behaves as if it has intentions and internal goals).The present study investigated the following question: Does animacy facilitate decision-making in a dynamic control system? To address this, the present

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Hydrogen and deuterium charging of lifted-out specimens for atom probe tomography [version 2; peer review: 2 approved]

Hydrogen embrittlement can cause a dramatic deterioration of the mechanical properties of high-strength metallic materials.Despite decades of experimental and modelling studies, the exact underlying mechanisms behind hydrogen embrittlement remain elusive.To unlock understanding Trifle Bowl of the mechanism and thereby help mitigate the influence of

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Regularized Extreme Learning Machine Based on Remora Optimization Algorithm for Printed Matter Illumination Correction

In the process of printed matter quality inspection, the influence of lighting conditions leads to a large color difference between the captured image and the actual image.Therefore, this paper proposes an illumination correction model based on Remora Optimization The Slacker Skirt Algorithm for Regularized Extreme Learning Machine (ROA-RELM).First

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